Fluplatin
Fluplatin is a prodrug composed of cisplatin and fluvastatin. Fluplatin has antitumor activity[1].
Product Specifications
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fluplatin.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C=C1)C2=C(N(C3=C2C=CC=C3)C(C)C)/C=C/C(CC(CC(O[Pt]([NH3])(OC(CC(CC(/C=C/C4=C(C5=C(N4C(C)C)C=CC=C5)C6=CC=C(C=C6)F)O)O)=O)[NH3])=O)O)O
Molecular Formula
C48H56F2N4O8Pt
Molecular Weight
1050.06
References & Citations
[1]Bi YY, et al. Nanoparticles targeting mutant p53 overcome chemoresistance and tumor recurrence in non-small cell lung cancer. Nat Commun. 2024 Mar 29;15 (1) :2759.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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