Clofarabine-5'-diphosphate (trisodium)
Clofarabine-5'-diphosphate trisodium (Clofarabine-DP trisodium) is the trisodium salt form of Clofarabine-5'-diphosphate. Clofarabine-5'-diphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-diphosphate trisodium can be further phorphorylated into Clofarabine-5'-triphosphate, and exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair[1].
Product Specifications
Product Name Alternative
Clofarabine-DP (trisodium)
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clofarabine-5-diphosphate-trisodium.html
Smiles
NC1=NC(Cl)=NC2=C1N=CN2[C@H]3[C@@H](F)[C@H](O)[C@@H](COP(OP(O[Na])(O[Na])=O)(O[Na])=O)O3
Molecular Formula
C10H10ClFN5Na3O9P2
Molecular Weight
529.58
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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