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Oxomemazine (Standard)

Product Specifications

UNSPSC Description

Oxomemazine (Standard) is the analytical standard of Oxomemazine. This product is intended for research and analytical applications. Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (Ki = 84 nM, M1 receptor) and low (Ki = 1.65 μM, M2 receptor) affinity sites[1]. Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment[2].

Target Antigen

Histamine Receptor; mGluR

Type

Reference compound

Related Pathways

GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/oxomemazine-standard.html

Smiles

CC(CN1C2=C(C=CC=C2)S(C3=CC=CC=C13)(=O)=O)CN(C)C

Molecular Weight

330.44

References & Citations

[1]S W Lee, et al.Selectivity of oxomemazine for the M1 muscarinic receptors.Arch Pharm Res. 1994 Dec;17(6):443-51.|[2]M S Siddegowda, et al.Oxomemazine hydro-chloride. Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o1875.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-136587R/Oxomemazine-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-136587R/

CAS Number

3689-50-7

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