SPAM1 Human Protein

<strong>SPAM1 Human Protein</strong>_x000D_ <strong>Catalog number:</strong> B2014116_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 52.1 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> HYA1, HYAL1, HYAL3, HYAL5, PH-20, SPAG15_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: G_mez-Torres MJ, Sez-Espinosa P, Manzano-Santiago P, Robles-G_mez L, Huerta-Retamal N, Aizpurua J. Sperm Adhesion Molecule 1 (SPAM1) Distribution in Selected Human Sperm by Hyaluronic Acid Test Biomedicines. 2022 Oct 13;10(10):2553._x000D_ 2: Dunn CA, Mager DL. Transcription of the human and rodent SPAM1 / PH-20 genes initiates within an ancient endogenous retrovirus BMC Genomics. 2005 Apr 1;6:47._x000D_ 3: Martin-DeLeon PA. Epididymal SPAM1 and its impact on sperm function Mol Cell Endocrinol. 2006 May 16;250(1-2):114-21._x000D_ 4: Chen H, Griffiths G, Galileo DS, Martin-DeLeon PA. Epididymal SPAM1 is a marker for sperm maturation in the mouse Biol Reprod. 2006 May;74(5):923-30._x000D_ 5: Park S, Kim YH, Jeong PS, Park C, Lee JW, Kim JS, Wee G, Song BS, Park BJ, Kim SH, Sim BW, Kim SU, Triggs-Raine B, Baba T, Lee SR, Kim E. SPAM1/HYAL5 double deficiency in male mice leads to severe male subfertility caused by a cumulus-oocyte complex penetration defect FASEB J. 2019 Dec;33(12):14440-14449._x000D_ 6: Griffiths GS, Galileo DS, Aravindan RG, Martin-DeLeon PA. Clusterin facilitates exchange of glycosyl phosphatidylinositol-linked SPAM1 between reproductive luminal fluids and mouse and human sperm membranes Biol Reprod. 2009 Sep;81(3):562-70._x000D_ 7: Martin-DeLeon PA, Zhang H, Morales CR, Zhao Y, Rulon M, Barnoski BL, Chen H, Galileo DS. Spam1-associated transmission ratio distortion in mice: elucidating the mechanism Reprod Biol Endocrinol. 2005 Aug 10;3:32._x000D_ 8: Reese KL, Aravindan RG, Griffiths GS, Shao M, Wang Y, Galileo DS, Atmuri V, Triggs-Raine BL, Martin-Deleon PA. Acidic hyaluronidase activity is present in mouse sperm and is reduced in the absence of SPAM1: evidence for a role for hyaluronidase 3 in mouse and human sperm Mol Reprod Dev. 2010 Sep;77(9):759-72._x000D_ 9: Evans EA, Zhang H, Martin-DeLeon PA. SPAM1 (PH-20) protein and mRNA expression in the epididymides of humans and macaques: utilizing laser microdissection/RT-PCR Reprod Biol Endocrinol. 2003 Aug 6;1:54._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15457544">10: Morales CR, Badran H, El-Alfy M, Men H, Zhang H, Martin-DeLeon PA. Cytoplasmic localization during testicular biogenesis of the murine mRNA for Spam1 (PH-20), a protein involved in acrosomal exocytosis Mol Reprod Dev. 2004 Dec;69(4):475-82. </a>_x000D_ _x000D_ <strong>Products Related to SPAM1 Human Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>