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Vismodegib (Standard)

Vismodegib (Standard) is the analytical standard of Vismodegib. This product is intended for research and analytical applications. Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2].

Product Specifications

CAS Number

879085-55-9

Product Name Alternative

GDC-0449 (Standard)

UNSPSC

12352005

Target

Autophagy; Hedgehog; Reference Standards

Type

Reference Standards

Related Pathways

Autophagy; Others; Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vismodegib-standard.html

Smiles

O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl

Molecular Formula

C19H14Cl2N2O3S

Molecular Weight

421.30

References & Citations

2+

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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