Histidine Buffer (0.2 M, pH 7.0)

<strong>Histidine Buffer (0.2 M, pH 7.0)</strong>_x000D_ <strong>Catalog number:</strong> B2017977_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.2 M_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8℃_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Holeček M. Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement Nutrients. 2020 Mar 22;12(3):848._x000D_ 2: Doyle Drbohlav LM, Sharma AN, Gopalrathnam G, Huang L, Bradley S. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems-Part 2 PDA J Pharm Sci Technol. 2019 Jul-Aug;73(4):320-330._x000D_ 3: Berenbrink M. Evolution of vertebrate haemoglobins: Histidine side chains, specific buffer value and Bohr effect Respir Physiol Neurobiol. 2006 Nov;154(1-2):165-84._x000D_ 4: Zhang Y, Schöneich C. Near UV light photo-degradation of histidine buffer: Mechanisms and role of Fe(III) Eur J Pharm Biopharm. 2023 Sep;190:231-241._x000D_ 5: Lei M, Quan C, Wang YJ, Kao YH, Schöneich C. Light-Induced Covalent Buffer Adducts to Histidine in a Model Protein Pharm Res. 2018 Feb 20;35(3):67._x000D_ 6: Kolhe P, Amend E, Singh SK. Impact of freezing on pH of buffered solutions and consequences for monoclonal antibody aggregation Biotechnol Prog. 2010 May-Jun;26(3):727-33._x000D_ 7: Brovč EV, Mravljak J, Šink R, Pajk S. Degradation of polysorbates 20 and 80 catalysed by histidine chloride buffer Eur J Pharm Biopharm. 2020 Sep;154:236-245._x000D_ 8: Zhang Y, Ballesteros ME, Schöneich C. Photo-induced site-specific oxidative fragmentation of IgG1 mediated by iron(III)-containing histidine buffer: Mechanistic studies and excipient effects Eur J Pharm Biopharm. 2023 Sep;190:121-130._x000D_ 9: Zhang Y, Schöneich C. Visible Light Induces Site-Specific Oxidative Heavy Chain Fragmentation of a Monoclonal Antibody (IgG1) Mediated by an Iron(III)-Containing Histidine Buffer Mol Pharm. 2023 Jan 2;20(1):650-662._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35946408">10: Saurabh S, Kalonia C, Li Z, Hollowell P, Waigh T, Li P, Webster J, Seddon JM, Lu JR, Bresme F. Understanding the Stabilizing Effect of Histidine on mAb Aggregation: A Molecular Dynamics Study Mol Pharm. 2022 Sep 5;19(9):3288-3303. </a>_x000D_ _x000D_ <strong>Products Related to Histidine Buffer (0.2 M, pH 7.0) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>