ATG12-IN-1
ATG12-IN-1 (compound 4) is an autophagy inhibitor (IC50=9 μM) targeting the ATG12-ATG3 protein-protein interaction, which can be used in cancer research[1].
Product Specifications
CAS Number
2950162-68-0
UNSPSC
12352211
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atg12-in-1.html
Smiles
OC(C1=CC=C2C(N=C(NC3=CC=CC(Cl)=C3)N4C2=NC(C5=CC=CC=C5)=C4)=C1)=O
Molecular Formula
C23H15ClN4O2
Molecular Weight
414.84
References & Citations
[1]Skach K, et al. Structure–activity relationship study of small-molecule inhibitor of Atg12-Atg3 protein–protein interaction[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 112: 129939.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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