(Rac) -Nebivolol-d2,15N
(Rac) -Nebivolol-d2,15N is 15N and deuterated labeled (Rac) -Nebivolol. (Rac) -Nebivolol ((Rac) -R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity[1][2].
Product Specifications
Product Name Alternative
(Rac) -R 065824-d2,15N
UNSPSC
12352005
Target
Adrenergic Receptor; Isotope-Labeled Compounds; NADPH Oxidase
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
FC1=CC=C2OC(C(C[15NH]CC(C3OC4=CC=C(C=C4C([2H])C3)F)O)O)CC([2H])C2=C1
Molecular Formula
C22H23D2F2 15NO4
Molecular Weight
408.44
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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