Isoxsuprine hydrochloride (Standard)

Isoxsuprine hydrochloride (Standard) is the analytical standard of Isoxsuprine hydrochloride. This product is intended for research and analytical applications. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.

Product Specifications

CAS Number

[579-56-6]

UNSPSC

12352005

Target

Adrenergic Receptor; iGluR; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/isoxsuprine-hydrochloride-standard.html

Smiles

OC(C(NC(C)COC1=CC=CC=C1)C)C2=CC=C(O)C=C2.[H]Cl

Molecular Formula

C18H24ClNO3

Molecular Weight

337.84

References & Citations

[1]Falkay G, et al. Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors. J Perinat Med. 1986;14 (2) :109-13.|[2]Kretschy N, et al. In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen. Br J Cancer. 2013 Feb 19;108 (3) :570-8.|[3]Hill JW, et al. Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening. PLoS One. 2014 May 7;9 (5) :e96761.