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Glycocholic acid-d4

Product Specifications

UNSPSC Description

Glycocholic acid-d4 is the deuterium labeled Glycocholic acid. Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways[1].

Target Antigen

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease;Others

Field of Research

Cancer

Purity

99.38

Solubility

DMSO : 100 mg/mL (ultrasonic;warming)

Smiles

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@]([C@H](C)CCC(NCC(O)=O)=O)([H])CC3)([C@@H](O)C[C@]2([H])[C@]4(C)[C@](C([2H])([2H])[C@H](O)C([2H])([2H])C4)([H])C1)C

Molecular Weight

469.65

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Lo YL, et al. Inhibit multidrug resistance and induce apoptosis by using glycocholic acid and epirubicin. Eur J Pharm Sci. 2008 Sep 2;35(1-2):52-67.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Clinical Information

No Development Reported

CAS Number

1201918-15-1

Curated Selection

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