HG1 Toxin
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, which has the activity of inhibiting potassium channel Kv1.3. HG1 Toxin also has the activity of inhibiting trypsin (Ki=107 nM) and can be used in the study of autoimmune diseases[1].
Product Specifications
UNSPSC
12352209
Target
Potassium Channel; Ser/Thr Protease
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hg1-toxin.html
Smiles
O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CC=CC=C4)C(NCC(NCC(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N6[C@@H](CCC6)C(N7[C@@H](CCC7)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(NCC(N8[C@@H](CCC8)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]5CCCNC(N)=N)=O)=O)=O)NC9=O)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CO)C(N[C@@H](CC%10=CC=CC=C%10)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N[C@@H](CC%12=CC=C(C=C%12)O)C(N[C@@H](CC%13=CC=CC=C%13)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(N[C@H]%14[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O%14)=O)C(N[C@@H](CC%15=CC=CC=C%15)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC%16=CNC=N%16)C(N[C@H]9CC%17=CNC=N%17)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC%18=O)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC%19=CC=CC=C%19)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC%20=CC=C(C=C%20)O)C(NCC(NC%18)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
Molecular Formula
C337H503N103O97S6
Molecular Weight
7741.62
References & Citations
[1]ZongYun Chen, et al. Hg1, novel peptide inhibitor specific for Kv1. 3 channels from first scorpion Kunitz-type potassium channel toxin family. Journal of biological chemistry 287.17 (2012) : 13813-13821.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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