SB-237376
SB-237376 is a blocker of potassium and calcium channels. SB-237376 inhibits the rapidly activating delayed rectifier potassium current I (Kr) (IC50: 0.42 μM) and blocks the L-type calcium current I (Ca, L) at high concentrations[1].
Product Specifications
CAS Number
[179258-62-9]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-237376.html
Smiles
COC1=C(OC)C=C(CCNCCCNC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=C1.Cl
Molecular Formula
C20H26ClN3O5
Molecular Weight
423.89
References & Citations
[1]Xu X, et al. Electrophysiologic effects of SB-237376: a new antiarrhythmic compound with dual potassium and calcium channel blocking action. J Cardiovasc Pharmacol. 2003 Mar;41 (3) :414-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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