Eribaxaban
Product Specifications
UNSPSC Description
Eribaxaban (PD-0348292) is an orally active and selective FXa inhibitor with a Ki value of 0.32 nM. Eribaxaban reduces thrombus formation[1][2].
Target Antigen
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/eribaxaban.html
Purity
98.52
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC(C=C1)=CC=C1Cl)N2[C@H](C[C@@H](OC)C2)C(NC3=CC=C(C=C3F)N(C=CC=C4)C4=O)=O
Molecular Weight
484.91
References & Citations
[1]Eriksson BI, et al. Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development. Clin Pharmacokinet. 2009;48(1):1-22.|[2]Karnicki K, et al. Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. Thromb Haemost. 2008 Apr;99(4):759-66.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10267/Eribaxaban-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10267/Eribaxaban-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
536748-46-6
Available Sizes
Curated Selection
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