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Eribaxaban

Eribaxaban (PD-0348292) is an orally active and selective FXa inhibitor with a Ki value of 0.32 nM. Eribaxaban reduces thrombus formation[1][2].

Product Specifications

CAS Number

[536748-46-6]

Product Name Alternative

PD-0348292

UNSPSC

12352005

Target

Factor Xa

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/eribaxaban.html

Purity

98.52

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC(C=C1)=CC=C1Cl)N2[C@H](C[C@@H](OC)C2)C(NC3=CC=C(C=C3F)N(C=CC=C4)C4=O)=O

Molecular Formula

C24H22ClFN4O4

Molecular Weight

484.91

References & Citations

[1]Eriksson BI, et al. Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development. Clin Pharmacokinet. 2009;48 (1) :1-22.|[2]Karnicki K, et al. Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis. Thromb Haemost. 2008 Apr;99 (4) :759-66.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-10267/Eribaxaban-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-10267/Eribaxaban-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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