Anti-inflammatory agent 77

Anti-inflammatory agent 77 (C12) is a β-cycloacinamide derived mono-carbonyl curcumin analog and an inhibitor of interleukin-6 (IL-6) . Anti-inflammatory agent 77 can be used in the study of wound healing[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-77.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C(C)(CCC1)C)/C=C2C(C(CCC/2)CC3=CC=C(C(OC)=C3)OC)=O

Molecular Formula

C25H34O3

Molecular Weight

382.54

References & Citations

[1]Forid MS, et al. Identification of β-cycloidal-derived mono-carbonyl curcumin analogs as potential interleukin-6 inhibitor to treat wound healing through QSAR, molecular docking, MD simulation, MM-GBSA calculation. J Biomol Struct Dyn. 2024 Mar 23:1-12.