MAPK14 antibody

MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T (H) 17 differentiation and inflammation (PMID:22231518) . It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell (PMID:21198398) . This protein has 4 isoforms produced by alternative splicing.

Mitogen-activated protein kinase 14 (MAP kinase 14, MAPK 14) |Cytokine suppressive anti-inflammatory drug-binding protein (CSAID-binding protein, CSBP) |MAP kinase MXI2|MAX-interacting protein 2|Mitogen-activated protein kinase p38 alpha (MAP kinase p38 alpha) |Stress-activated protein kinase 2a (SAPK2a) |MAPK14|CSBP|CSBP1|CSBP2|CSPB1|MXI2|SAPK2A