Human Citrullinated Nucleophosmin

<strong>Human Citrullinated Nucleophosmin</strong>_x000D_ <strong>Catalog number:</strong> B2016741_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 34.7 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Choudhury RH, Symonds P, Paston SJ, Daniels I, Cook KW, Gijon M, Metheringham RL, Brentville VA, Durrant LG. PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy J Immunother Cancer. 2022 Feb;10(2):e003526._x000D_ 2: Zhai Q, Wang L, Zhao P, Li T. Role of citrullination modification catalyzed by peptidylarginine deiminase 4 in gene transcriptional regulation Acta Biochim Biophys Sin (Shanghai). 2017 Jul 1;49(7):567-572._x000D_ 3: Tanikawa C, Ueda K, Nakagawa H, Yoshida N, Nakamura Y, Matsuda K. Regulation of protein Citrullination through p53/PADI4 network in DNA damage response Cancer Res. 2009 Nov 15;69(22):8761-9._x000D_ 4: Na J, Lee CH, Chung JK, Youn H. Overexpression of Both Human Sodium Iodide Symporter (NIS) and BRG1-Bromodomain Synergistically Enhances Radioiodine Sensitivity by Stabilizing p53 through NPM1 Expression Int J Mol Sci. 2023 Feb 1;24(3):2761._x000D_ 5: Hagiwara T, Nakashima K, Hirano H, Senshu T, Yamada M. Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes Biochem Biophys Res Commun. 2002 Jan 25;290(3):979-83._x000D_ 6: Hao G, Wang D, Gu J, Shen Q, Gross SS, Wang Y. Neutral loss of isocyanic acid in peptide CID spectra: a novel diagnostic marker for mass spectrometric identification of protein citrullination J Am Soc Mass Spectrom. 2009 Apr;20(4):723-7._x000D_ 7: Cela I, Di Matteo A, Federici L. Nucleophosmin in Its Interaction with Ligands Int J Mol Sci. 2020 Jul 10;21(14):4885._x000D_ 8: Sekhar KR, Freeman ML. Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment Cancer Res. 2023 May 15;83(10):1573-1580._x000D_ 9: Grisendi S, Mecucci C, Falini B, Pandolfi PP. Nucleophosmin and cancer Nat Rev Cancer. 2006 Jul;6(7):493-505._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35621728">10: Shi Y, Xue Y, Wang C, Yu L. Nucleophosmin 1: from its pathogenic role to a tantalizing therapeutic target in acute myeloid leukemia Hematology. 2022 Dec;27(1):609-619. </a>_x000D_ _x000D_ <strong>Products Related to Human Citrullinated Nucleophosmin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>