Human ACAT1 Protein

<strong>Human ACAT1 Protein </strong>_x000D_ <strong>Catalog number:</strong> B2011008_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> na_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical studies_x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> ACAT1, ACAT protein, ACAT 1 protein, ACAT 1, T2 protein, MAT protein, ACAT-1 protein, THIL protein, ACAT-1, acetyl-CoA acetyltransferase 1 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nugent AA, Lin K, van Lengerich B, Lianoglou S, Przybyla L, Davis SS, Llapashtica C, Wang J, Kim DJ, Xia D, Lucas A, Baskaran S, Haddick PCG, Lenser M, Earr TK, Shi J, Dugas JC, Andreone BJ, Logan T, Solanoy HO, Chen H, Srivastava A, Poda SB, Sanchez PE, Watts RJ, Sandmann T, Astarita G, Lewcock JW, Monroe KM, Di Paolo G. TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge Neuron. 2020 Mar 4;105(5):837-854.e9._x000D_ 2: Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong CCL, Yan N. Structural basis for catalysis and substrate specificity of human ACAT1 Nature. 2020 May;581(7808):333-338._x000D_ 3: Yu XH, Fu YC, Zhang DW, Yin K, Tang CK. Foam cells in atherosclerosis Clin Chim Acta. 2013 Sep 23;424:245-52._x000D_ 4: Szántó M, Gupte R, Kraus WL, Pacher P, Bai P. PARPs in lipid metabolism and related diseases Prog Lipid Res. 2021 Nov;84:101117._x000D_ 5: Goudarzi A. The recent insights into the function of ACAT1: A possible anti-cancer therapeutic target Life Sci. 2019 Sep 1;232:116592._x000D_ 6: Zhang CY, Yuan WG, He P, Lei JH, Wang CX. Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets World J Gastroenterol. 2016 Dec 28;22(48):10512-10522._x000D_ 7: Gu L, Zhu Y, Lin X, Tan X, Lu B, Li Y. Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis Oncogene. 2020 Mar;39(11):2437-2449._x000D_ 8: Yang W, Bai Y, Xiong Y, Zhang J, Chen S, Zheng X, Meng X, Li L, Wang J, Xu C, Yan C, Wang L, Chang CC, Chang TY, Zhang T, Zhou P, Song BL, Liu W, Sun SC, Liu X, Li BL, Xu C. Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism Nature. 2016 Mar 31;531(7596):651-5._x000D_ 9: Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN. Mechanisms of foam cell formation in atherosclerosis J Mol Med (Berl). 2017 Nov;95(11):1153-1165._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32433613">10: Long T, Sun Y, Hassan A, Qi X, Li X. Structure of nevanimibe-bound tetrameric human ACAT1 Nature. 2020 May;581(7808):339-343. </a>_x000D_ _x000D_ <strong>Products Related to Human ACAT1 Protein</strong><a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>