PFKFB3 antibody
Product Specifications
Background
PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.
Synonyms
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3, PFK/FBPase 3) |6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme|Renal carcinoma antigen NY-REN-56|iPFK-2|PFKFB3
Gene ID
5209
UniProt
Q16875
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Target
PFKFB3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
243-520aa
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15145164 1 Vial
Lentiviral human WASL shRNA (UAS) - Lentiviral human WASL shRNA (UAS, RFP) (100)
Ask
View Details 
GTR15140314 1 Vial
Lentiviral mouse Stip1 shRNA (UAS) - Lentiviral mouse Stip1 shRNA (UAS, GFP) plasmid
Ask
View Details 