Mutabilol

Product Specifications

UNSPSC Description

Mutabilol (compound 1) is a potent p-glycoprotein (P-gp) regulator. Mutabilol is a nature product could be isolated from Plectranthus mutabilis leaves. Mutabilol increases the P-gp expression in NCI-H460/R cells[1].

Target Antigen

P-glycoprotein

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mutabilol.html

Solubility

10 mM in DMSO

Smiles

O[C@@]12C(C(C(C3=C2C(O)=C(C(C(C)C)=C3)O)=O)=O)C(C)(C)CCC1

Molecular Weight

332.39

References & Citations

[1]Ntungwe EN, et al. C20-nor-Abietane and Three Abietane Diterpenoids from Plectranthus mutabilis Leaves as P-Glycoprotein Modulators. ACS Med Chem Lett. 2022 Mar 11;13(4):674-680.