Mutabilol
Product Specifications
UNSPSC Description
Mutabilol (compound 1) is a potent p-glycoprotein (P-gp) regulator. Mutabilol is a nature product could be isolated from Plectranthus mutabilis leaves. Mutabilol increases the P-gp expression in NCI-H460/R cells[1].
Target Antigen
P-glycoprotein
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mutabilol.html
Solubility
10 mM in DMSO
Smiles
O[C@@]12C(C(C(C3=C2C(O)=C(C(C(C)C)=C3)O)=O)=O)C(C)(C)CCC1
Molecular Weight
332.39
References & Citations
[1]Ntungwe EN, et al. C20-nor-Abietane and Three Abietane Diterpenoids from Plectranthus mutabilis Leaves as P-Glycoprotein Modulators. ACS Med Chem Lett. 2022 Mar 11;13(4):674-680.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10562/Mutabilol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10562/
Clinical Information
No Development Reported
Curated Selection
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