α-Glucosidase-IN-64

α-Glucosidase-IN-64 (compound 10) is a potent α-glucosidase inhibitor with an IC50 value of 8.62 µM. α-Glucosidase-IN-64 is a polycyclic polyprenylated acylphloroglucinol that can be isolated from hypericum beanii[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-64.html

Smiles

O=C(C1=C(O)C(C[C@]([C@@H](C(C)(O)C)CC2)([H])[C@]2(C)O3)=C3C(C/C=C(C)/C)(C/C=C(C)/C)C1=O)C4=CC=CC=C4

Molecular Formula

C33H42O5

Molecular Weight

518.68

References & Citations

[1]Hu RD, et al. New α-Glucosidase Inhibitors from the Whole Plant of Hypericum beanii Based on Ligand Fishing and Molecular Networking Analysis. J Agric Food Chem. 2024 May 22;72 (20) :11452-11464.