CR-1-30-B
CR-1-30-B is an inactive enantiomer of CR-1-31-B. CR-1-30-B, as a control, is inactive against eIF4A and has no apparent effect on the induction of MUC1-C translation[1].
Product Specifications
CAS Number
[1352914-53-4]
UNSPSC
12352005
Target
Drug Isomer; Mucin
Type
Reference compound
Related Pathways
Immunology/Inflammation; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cr-1-30-b.html
Purity
99.92
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C([C@@H]([C@@H]1C2=CC=CC=C2)[C@H](O)[C@@]3(O)[C@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)NOC
Molecular Formula
C28H29NO8
Molecular Weight
507.53
References & Citations
[1]Jin C, et al. Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein [published correction appears in Oncogene. 2021 May;40 (18) :3347]. Oncogene. 2013;32 (17) :2179-2188.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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