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ALS-I-41

ALS-I-41 is a novel, potent and selective oxytocin receptor antagonist with the potential to modulate biological activities related to social behavior and mental disorders. ALS-I-41 is being evaluated for behavioral pharmacology experiments in non-human primates and can be administered via intranasal or intramuscular injection. The central nervous system penetration and metabolic rate of ALS-I-41 were studied by mass spectrometry analysis in cerebrospinal fluid and plasma of macaque monkeys[1].

Product Specifications

CAS Number

[1369357-99-2]

UNSPSC

12352005

Target

Oxytocin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/als-i-41.html

Smiles

O=C1N(C2CCN(CC2)C(CC3=CC=C(C=C3OCCF)OC4CCN(S(=O)(C)=O)CC4)=O)C5=C(CC1)C=CC=C5

Molecular Formula

C30H38FN3O6S

Molecular Weight

587.70

References & Citations

[1]An evaluation of central penetration from a peripherally administered oxytocin receptor selective antagonist in nonhuman primates

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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