HER2-IN-17
HER2-IN-17 (Compound 2) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 IC50 [1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/her2-in-17.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CC(C1)N2C=C(C=N2)C3=C4C(NC5=CC=C(C(C)=C5)OC6=CC7=NC=NN7C=C6)=NC=NN4C=C3)=O
Molecular Formula
C28H24N10O2
Molecular Weight
532.56
References & Citations
[1]Svitlana KULYK, et al., Compounds and methods for modulating her2. Patent WO2024044570.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2
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