Polymyxin deacylase
Polymyxin deacylase (Polymyxin acylase) is an N-myristoyl lyase. Polymyxin deacylase can deacylate polymyxin antibiotics and long-chain fatty acyl groups of proteins and peptides. Polymyxin deacylase exhibits antitumor activity against oral epithelial cancer cells. Polymyxin deacylase can be used in research on oral epithelial cancer and other cancers[1][2].
Product Specifications
CAS Number
111174-43-7
Product Name Alternative
Polymyxin acylase
UNSPSC
12352204
Target
Biochemical Assay Reagents
Type
Enzyme
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/polymyxin-deacylase.html
Solubility
10 mM in DMSO
Smiles
[Polymyxindeacylase]
References & Citations
[1]Yasuda N, et al. In vitro antitumor activity of polymyxin acylase from Pseudomonas sp. M-6-3. Biol Pharm Bull. 1995 Apr;18 (4) :615-7. |[2]Misumi S, et al. Determination of N-myristoyl peptide sequence both by MALDI TOF MASS and with an N-myristoyl cleaving enzyme (polymyxin acylase) . Biochem Biophys Res Commun. 1995 Dec 14;217 (2) :632-9.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Frequently Asked Questions
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