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Polymyxin deacylase

Polymyxin deacylase (Polymyxin acylase) is an N-myristoyl lyase. Polymyxin deacylase can deacylate polymyxin antibiotics and long-chain fatty acyl groups of proteins and peptides. Polymyxin deacylase exhibits antitumor activity against oral epithelial cancer cells. Polymyxin deacylase can be used in research on oral epithelial cancer and other cancers[1][2].

Product Specifications

CAS Number

111174-43-7

Product Name Alternative

Polymyxin acylase

UNSPSC

12352204

Target

Biochemical Assay Reagents

Type

Enzyme

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/polymyxin-deacylase.html

Solubility

10 mM in DMSO

Smiles

[Polymyxindeacylase]

References & Citations

[1]Yasuda N, et al. In vitro antitumor activity of polymyxin acylase from Pseudomonas sp. M-6-3. Biol Pharm Bull. 1995 Apr;18 (4) :615-7. |[2]Misumi S, et al. Determination of N-myristoyl peptide sequence both by MALDI TOF MASS and with an N-myristoyl cleaving enzyme (polymyxin acylase) . Biochem Biophys Res Commun. 1995 Dec 14;217 (2) :632-9.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Frequently Asked Questions

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