6-Bn-cAMP
6-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinase (PKA) which does not activate Epac. 6-Bn-cAMP increases hydrolytic stability against PDE, esterases, amidases and considerably higher membrane permeability compared to cAMP[1].
Product Specifications
CAS Number
32115-08-5
Product Name Alternative
N6-Benzyladenosine-3',5'-cyclic monophosphate
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-bn-camp.html
Smiles
O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C=NC4=C3N=CN=C4NCC5=CC=CC=C5
Molecular Formula
C17H18N5O6P
Molecular Weight
419.33
References & Citations
[1]Pepe S, et al. Effects of 8-chloroadenosine 3',5'-monophosphate and N6-benzyl-cyclic adenosine 5'-monophosphate on cell cycle kinetics of HL-60 leukemia cells. Cancer Res. 1991 Dec 1;51 (23 Pt 1) :6263-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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