Ac-rC Phosphoramidite-13C2, d1

Ac-rC Phosphoramidite-13C2, d1 is deuterium and 13C-labeled Ac-rC Phosphoramidite (HY-W042357) . Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA) .

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Others

Applications

Cancer-programmed cell death

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[13C@H](N5C(N=C(NC(C)=O)C([2H])=[13CH]5)=O)O4

Molecular Formula

C45 13C2H63DN5O9PSi

Molecular Weight

905.09

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59 (23) :2154-2170.