Ac-rC Phosphoramidite-13C2,d1
Product Specifications
UNSPSC Description
Ac-rC Phosphoramidite-13C2,d1 is deuterium and 13C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
Target Antigen
DNA/RNA Synthesis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage;Others
Applications
Cancer-programmed cell death
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[13C@H](N5C(N=C(NC(C)=O)C([2H])=[13CH]5)=O)O4
Molecular Weight
905.09
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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