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Robustine

Robustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1].

Product Specifications

CAS Number

2255-50-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphodiesterase (PDE)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/robustine.html

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C2N=C(OC=C3)C3=C(OC)C2=CC=C1

Molecular Formula

C12H9NO3

Molecular Weight

215.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Nam KW, et al. Inhibitory effects of furoquinoline alkaloids from Melicope confusa and Dictamnus albus against human phosphodiesterase 5 (hPDE5A) in vitro. Arch Pharm Res. 2005 Jun;28 (6) :675-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

PDE5

Available Sizes

Frequently Asked Questions

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