Robustine
Robustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1].
Product Specifications
CAS Number
[2255-50-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/robustine.html
Purity
99.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C2N=C(OC=C3)C3=C(OC)C2=CC=C1
Molecular Formula
C12H9NO3
Molecular Weight
215.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Nam KW, et al. Inhibitory effects of furoquinoline alkaloids from Melicope confusa and Dictamnus albus against human phosphodiesterase 5 (hPDE5A) in vitro. Arch Pharm Res. 2005 Jun;28 (6) :675-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PDE5
Available Sizes
Curated Selection
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