Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo
Product Specifications
UNSPSC Description
Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo is an E3 Ligase Ligand-Linker Conjugate. Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo can be used to synthesize PROTAC SMARCA2/4-degrader-1 (HY-159452)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/ac-nh-s-r-s-ahpc-co-cyclohexane-pyrimidine-diazabicyclo.html
Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(C=C(C3=C(N=CS3)C)C=C2)NC(C)=O)=O)[C@H](C(C)(C)C)NC([C@H](CC4)CC[C@@H]4C5=CN=C(N=C5)N6C7CNCC6CC7)=O
Molecular Weight
786.00
References & Citations
[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159593/Ac-NH-S-R-S-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159593/
Clinical Information
No Development Reported
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