Tec-IN-6
Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC50 of 8.9 μM (His-FGF2/GST-NΔ173 Tec) [1].
Product Specifications
CAS Number
923762-87-2
UNSPSC
12352005
Target
FGFR; Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tec-in-6.html
Smiles
O=C(OCC(N=C1N2C(C)=CC=C1)=CC2=O)C3=C(C(C(OC)=O)=C(N3)C)C
Molecular Formula
C19H19N3O5
Molecular Weight
369.37
References & Citations
[1]Giuseppe La Venuta, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291 (34) :17787-803.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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