Tec-IN-6

Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC50 of 8.9 μM (His-FGF2/GST-NΔ173 Tec) [1].

Product Specifications

CAS Number

[923762-87-2]

UNSPSC

12352005

Target

FGFR; Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tec-in-6.html

Smiles

O=C(OCC(N=C1N2C(C)=CC=C1)=CC2=O)C3=C(C(C(OC)=O)=C(N3)C)C

Molecular Formula

C19H19N3O5

Molecular Weight

369.37

References & Citations

[1]Giuseppe La Venuta, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291 (34) :17787-803.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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