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RdRP-IN-8

RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC50=0.13 μM) [1].

Product Specifications

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rdrp-in-8.html

Smiles

O=C(C1=C(O)C=C([N+]([O-])=O)C=C1)NC(S2)=C(C(NC3=CC=CC=C3O)=O)C4=C2CCCCC4

Molecular Formula

C23H21N3O6S

Molecular Weight

467.49

References & Citations

[1]Bonomini, et al. "Optimization of Potent, Broad-spectrum, and Specific Anti-influenza Compounds Targeting RNA Polymerase PA-PB1 heterodimerization." European Journal of Medicinal Chemistry (2024) : 116737.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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