Telotristat (besilate)
Telotristat besilate is a potent tryptophan hydroxylase inhibitor with an in vivo IC50 of 0.028 μM.
Product Specifications
CAS Number
1374745-52-4
UNSPSC
12352005
Target
Tryptophan Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/telotristat-besilate.html
Smiles
N[C@H](C(O)=O)CC1=CC=C(C=C1)C2=NC(N)=NC(O[C@@H](C(F)(F)F)C3=CC=C(C=C3N4N=C(C=C4)C)Cl)=C2.O=S(C5=CC=CC=C5)(O)=O
Molecular Formula
C31H28ClF3N6O6S
Molecular Weight
705.10
References & Citations
[1]Lapuerta P, et al. Telotristat etiprate, a novel inhibitor of serotonin synthesis for the treatment of carcinoid syndrome. Clin. Invest. (Lond.) (2015) 5 (5), 447–456|[2]US20080153852
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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