UZH2
UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
Product Specifications
CAS Number
[2756566-45-5]
Product Name Alternative
Xenazoic acid; CV58912,Clodantoin
UNSPSC
12352005
Target
METTL3
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uzh2.html
Purity
98.91
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CNC1=NC=NC(N2CCC3(CN(CC(N3)=O)C4=C(C=C(C(F)=C4)CN5CCC(C)(CC5)C)F)CC2)=C1
Molecular Formula
C27H37F2N7O
Molecular Weight
513.63
References & Citations
[1]Dolbois A, et al. 1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors. J Med Chem. 2021 Sep 9;64 (17) :12738-12760.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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