HCC-1/CCL14, Human (74a.a, His)
HCC-1/CCL14 Protein, Human (74a.a, His) is a CC chemokine with weak activity against human monocytes, promotes monocyte, eosinophil and T-lymphocyte chemotaxis, and mediates allergic airway inflammation and cancer. HCC-1/CCL14 Protein, Human (74a.a, His) is a recombinant human HCC-1/CCL14 (T20-N93) expressed by E. coli with a his tag at the nitrogen end[1][2].
Product Specifications
Product Name Alternative
HCC-1/CCL14 Protein, Human (74a.a, His), Human, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/hcc-1-ccl14-protein-human-74a-a-his.html
Molecular Formula
6358 (Gene_ID) Q16627-1 (T20-N93) (Accession)
Molecular Weight
Approximately 12 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
[1]Siyao Wang, et al. Glycosylation Regulates N-Terminal Proteolysis and Activity of the Chemokine CCL14. ACS Chem Biol. 2021 Jun 18;16 (6) :973-981.|[2]Mengxuan Zhu, et al. CCL14 serves as a novel prognostic factor and tumor suppressor of HCC by modulating cell cycle and promoting apoptosis. Cell Death Dis. 2019 Oct 22;10 (11) :796.|[3]Natalie J Hannan, et al. CX3CL1 and CCL14 regulate extracellular matrix and adhesion molecules in the trophoblast: potential roles in human embryo implantation. Biol Reprod. 2008 Jul;79 (1) :58-65.
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
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