L11204
L11204 (DL-204-IT) is a potent inhibitor of prostaglandin metabolism. L11204 inhibits PMS-induced superovulation and reduced the number of recoverable ova in the oviducts of hamsters. L11204 also inhibits chorionic gonadotrophin-induced ovarian hypertrophy and steroidogenesi in rats. L11204 is promising for research of reproductive system disorders[1][2].
Product Specifications
CAS Number
[55308-64-0]
Product Name Alternative
DL-204-IT
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l11204.html
Smiles
CCOC1=CC(C2=NN(CCC3=C4C=CC=C3)C4=N2)=CC=C1
Molecular Formula
C18H17N3O
Molecular Weight
291.35
References & Citations
[1]Valenzuela G, et al. Effect of inhibitors of prostaglandin synthesis and metabolism on ovum transport in the rabbit. Fertil Steril. 1977 Sep;28 (9) :992-7. |[2]Lerner L J, et al. Inhibition of superovulation and alteration of ova transportation in hamsters by prostaglandin and DL-204-IT, an anti-fertility agent[J]. Prostaglandins and Medicine, 1981, 6 (4) : 369-374.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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