Scholaricine

Scholaricine (compound 13) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].

Product Specifications

CAS Number

[99694-90-3]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/scholaricine.html

Solubility

10 mM in DMSO

Smiles

COC(C1=C2[C@]3(C4=CC=CC(O)=C4N2)[C@@]5([H])N(C[C@]([C@]1([H])C5)([H])[C@@H](O)C)CC3)=O

Molecular Formula

C20H24N2O4

Molecular Weight

356.42

References & Citations

[1]Shin-Jowl Tan , et al. Strychnan and secoangustilobine A type alkaloids from Alstonia spatulata. Revision of the C-20 configuration of scholaricine. J Nat Prod. 2010, 73, 11.