Posatirelin
Posatirelin, a TRH analog, increases monoamine metabolites in the cerebral cortex, nucleus accumbens, and striatum, and possibly exerts CNS activating effects through a modification of several neurotransmitter systems[1].
Product Specifications
CAS Number
78664-73-0
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/posatirelin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC(CCC1)=O)N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(N)=O)=O
Molecular Formula
C17H28N4O4
Molecular Weight
352.43
References & Citations
[1]G Benzi, et al. Age-related changes by hypoxia and TRH analogue on synaptic ATPase activities. Neurobiol Aging. 1994 Jul-Aug;15 (4) :409-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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