Posatirelin
Posatirelin, a TRH analog, increases monoamine metabolites in the cerebral cortex, nucleus accumbens, and striatum, and possibly exerts CNS activating effects through a modification of several neurotransmitter systems[1].
Product Specifications
CAS Number
78664-73-0
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/posatirelin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC(CCC1)=O)N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(N)=O)=O
Molecular Formula
C17H28N4O4
Molecular Weight
352.43
References & Citations
[1]G Benzi, et al. Age-related changes by hypoxia and TRH analogue on synaptic ATPase activities. Neurobiol Aging. 1994 Jul-Aug;15 (4) :409-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH030612 100 µg
Recombinant Human SELM/Selenoprotein M Protein (His Tag)
Sign In for Pricing
View Details 
LC434100 20 µg
Asialoglycoprotein Receptor 1 (ASGR1) (NM_001197216) Human Over-expression Lysate
Sign In for Pricing
View Details 
