Cyclin E2 Recombinant Mouse Monoclonal Antibody [40-89-R]
Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27 (Kip1) and p21 (Cip1). It plays a role in the G1/S portion of the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CCNE2
Swiss Prot
O96020 Human
Cellular Locus
Nucleus.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Cyclin E2 aa 1-50 / 404.
Isotype
IgG
Clone
40-89-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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