[DAla4] Substance P (4-11)
[DAla4] Substance P (4-11) is an analog of Substance P that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (HY-P0006) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1].
Product Specifications
CAS Number
81381-50-2
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dala4-substance-p-4-11.html
Solubility
10 mM in DMSO
Smiles
CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](N)C)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O
Molecular Formula
C44H65N11O10S
Molecular Weight
940.12
References & Citations
[1]M A Cascieri, et al. Demonstration of two distinct tachykinin receptors in rat brain cortex. J Biol Chem. 1985 Feb 10;260 (3) :1501-7.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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