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Nerol-d2

Product Specifications

UNSPSC Description

Nerol-d2 is deuterated labeled Octanal (HY-N8015). Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells[1].

Target Antigen

Apoptosis; Endogenous Metabolite; Fungal; Isotope-Labeled Compounds; Mitochondrial Metabolism; Reactive Oxygen Species

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

C/C(C)=C\CC/C(C)=C\C([2H])([2H])O

Molecular Weight

156.26

References & Citations

[1]Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca<sup>2+</sup> overload in saprotrophic fungus <i>Aspergillus flavus</i>. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672.|[2]Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca<sup>2+</sup> and ROS in <i>Candida albicans</i>. Int J Biochem Cell Biol. 2017 Apr;85:114-122.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

CAS Number

32637-85-7

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