SARS-CoV-2-IN-34
SARS-CoV-2-IN-34 (S-20-1) is a blood brain barrier penetrable pan-coronavirus (CoV) fusion inhibitor with broad-spectrum inhibitory activity. SARS-CoV-2-IN-34 effectively inhibits infection by pseudotyped and authentic SARS-CoV-2, and pseudotyped variants of concern (VOCs) . SARS-CoV-2-IN-34 shows high affinity to RBD in S1 and HR1 domain in S2 of SARS-CoV-2 S protein. SARS-CoV-2-IN-34 can be used for the research of infection[1].
Product Specifications
CAS Number
3029103-37-2
UNSPSC
12352209
Target
SARS-CoV
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-in-34.html
Solubility
10 mM in DMSO
Smiles
CC(C[C@H]1CN(CC(N[C@H](CN(CC(N[C@H](CN(C(CCSCC2=CC=C(C(N[C@H](CN(CC(N1)=O)C(CCCN)=O)CC3=CC=CC=C3)=O)C=C2)=O)CC(NCCC(N[C@H](CN(C(CCC(O)=O)=O)CC(N)=O)CCC(O)=O)=O)=O)CC4=CC=CC=C4)=O)C(CC5=CC=C6C=CC=CC6=C5)=O)CC7=CC=CC=C7)=O)C(CCC8CCCCC8)=O)C
Molecular Formula
C91H119N13O16S
Molecular Weight
1683.06
References & Citations
[1]Xue S, et al. A novel cyclic γ-AApeptide-based long-acting pan-coronavirus fusion inhibitor with potential oral bioavailability by targeting two sites in spike protein. Cell Discov. 2022 Sep 8;8 (1) :88.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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