STAT3-IN-24, cell-permeable
STAT3-IN-24, cell-permeable (PpYLKTK-mts) is a STAT3 peptide inhibitor. STAT3-IN-24, cell-permeable inhibits recruitment of STAT3 to Jak2 and phosphorylation of Y705, thus preventing the dimerization and the nuclear translocation of STAT3[1].
Product Specifications
CAS Number
[400628-16-2]
Product Name Alternative
PpYLKTK-mts; STAT3 PI
UNSPSC
12352209
Target
STAT
Type
Peptides
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-24-cell-permeable.html
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C92H157N20O24P
Molecular Weight
1958.32
References & Citations
[1]Buettner C, et al. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006 Jul;4 (1) :49-60.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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