STAT3-IN-24, cell-permeable
Product Specifications
UNSPSC Description
STAT3-IN-24, cell-permeable (PpYLKTK-mts) is a STAT3 peptide inhibitor. STAT3-IN-24, cell-permeable inhibits recruitment of STAT3 to Jak2 and phosphorylation of Y705, thus preventing the dimerization and the nuclear translocation of STAT3[1].
Target Antigen
STAT
Type
Peptides
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-24-cell-permeable.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)OP(O)(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]4NCCC4
Molecular Weight
1958.32
References & Citations
[1]Buettner C, et al. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006 Jul;4(1):49-60.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10114/STAT3-IN-24-cell-permeable-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10114/
Clinical Information
No Development Reported
CAS Number
400628-16-2
Curated Selection
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