Palmitoyl serotonin

Palmitoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin, antagonist of FAAH. Palmitoyl serotonin inhibits L-3,4-dihydroxyphenylalanine (HY-N0304) induced abnormal involuntary movements. Palmitoyl serotonin has the potential for the research of parkinson's disease (PD) [1][2].

Product Specifications

CAS Number

[212707-51-2]

Product Name Alternative

PA-5HT

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/palmitoyl-serotonin.html

Purity

99.0

Solubility

DMF : 30 mg/mL (ultrasonic; warming)

Smiles

CCCCCCCCCCCCCCCC(NCCC1=CNC2=C1C=C(O)C=C2)=O

Molecular Formula

C26H42N2O2

Molecular Weight

414.62

Precautions

H315, H319, H335

References & Citations

[1]Park HY, et al. Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson Model. Exp Neurobiol. 2016 Aug;25 (4) :174-84.|[2]Muthubharathi BC, et al. Physiological and Metabolite Alterations Associated with Neuronal Signals of Caenorhabditis elegans during Cronobacter sakazakii Infections. ACS Chem Neurosci. 2021 Nov 17;12 (22) :4336-4349.