Palmitoleoyl-CoA (triammonium)
Product Specifications
UNSPSC Description
Palmitoleoyl-CoA triammonium is the triammonium salt form of Palmitoleoyl-CoA (HY-137782). Palmitoleoyl-CoA triammonium can be activated and transported into the mitochondria for metabolism, specifically for β-oxidation. Palmitoleoyl-CoA triammonium induces the cardiac mitochondrial membrane permeability transition, which causes mitochondrial dysfunction. Palmitoleoyl-CoA triammonium regulates metabolism via allosteric control of AMPK β1-isoforms[1][2].
Target Antigen
Biochemical Assay Reagents
Type
Enzyme
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/palmitoleoyl-coa-triammonium.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(CCCCCCC/C=C\CCCCCC)=O)=O)=O)O)C)=O)=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2.N.N.N
Molecular Weight
1055.02
References & Citations
[1]Stephen L Pinkosky, et al. Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms. Nat Metab. 2020 Sep;2(9):873-881.|[2]Oyanagi E, et al., Palmitoleic acid induces the cardiac mitochondrial membrane permeability transition despite the presence of L-carnitine. Biochem Biophys Res Commun. 2015 Jul 17-24;463(1-2):29-36.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137782A/Palmitoleoyl-CoA-triammonium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137782A/
Clinical Information
No Development Reported
CAS Number
1246304-41-5
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