Antibacterial agent 254
Antibacterial agent 254 (Compound 2) is a dispersion sensor (DspS) activator that disperses Pseudomonas aeruginosa biofilms. Antibacterial agent 254 can dislodge 7-day P. aeruginosa biofilms at 50 μM. Antibacterial agent 254 also enhances the effects of Ciprofloxacin against P. aeruginosa and increases the expression of matrix-degrading enzyme genes pelA, pslG and eddA[1].
Product Specifications
CAS Number
2418779-48-1
UNSPSC
12352211
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-254.html
Smiles
OC(C1=CC(CC(N[C@@H]2CC[C@H]2O)=O)=CC=C1)=O
Molecular Formula
C13H15NO4
Molecular Weight
249.26
References & Citations
[1]Koh CMM, et al. Virtual Screening Uncovers DspS Activators That Disperse Pseudomonas aeruginosa Biofilms. ACS Infect Dis. 2024 Oct 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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