Human CERT Protein

<strong>Human CERT Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011923_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.5 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Goodpasture protein binding protein protein, CERTL protein, STARD11 protein, FLJ20597 protein, START domain containing 11 protein, Ceramide transporter protein, Collagen type IV alpha 3 (Goodpasture protein) binding protein protein, CERT protein, alpha 3_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chung LH, Liu D, Liu XT, Qi Y. Ceramide Transfer Protein (CERT): An Overlooked Molecular Player in Cancer Int J Mol Sci. 2021 Dec 7;22(24):13184._x000D_ 2: Kumagai K, Hanada K. Structure, functions and regulation of CERT, a lipid-transfer protein for the delivery of ceramide at the ER-Golgi membrane contact sites FEBS Lett. 2019 Sep;593(17):2366-2377._x000D_ 3: Hanada K. Co-evolution of sphingomyelin and the ceramide transport protein CERT Biochim Biophys Acta. 2014 May;1841(5):704-19._x000D_ 4: Agaisse H, Derré I. Expression of the effector protein IncD in Chlamydia trachomatis mediates recruitment of the lipid transfer protein CERT and the endoplasmic reticulum-resident protein VAPB to the inclusion membrane Infect Immun. 2014 May;82(5):2037-47._x000D_ 5: Kumagai K, Kawano-Kawada M, Hanada K. Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells J Biol Chem. 2014 Apr 11;289(15):10748-10760._x000D_ 6: Charruyer A, Bell SM, Kawano M, Douangpanya S, Yen TY, Macher BA, Kumagai K, Hanada K, Holleran WM, Uchida Y. Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation J Biol Chem. 2008 Jun 13;283(24):16682-92._x000D_ 7: Kumagai K, Elwell CA, Ando S, Engel JN, Hanada K. Both the N- and C- terminal regions of the Chlamydial inclusion protein D (IncD) are required for interaction with the pleckstrin homology domain of the ceramide transport protein CERT Biochem Biophys Res Commun. 2018 Nov 10;505(4):1070-1076._x000D_ 8: Murakami H, Tamura N, Enomoto Y, Shimasaki K, Kurosawa K, Hanada K. Intellectual disability-associated gain-of-function mutations in CERT1 that encodes the ceramide transport protein CERT PLoS One. 2020 Dec 21;15(12):e0243980._x000D_ 9: Hanada K, Kumagai K, Tomishige N, Kawano M. CERT and intracellular trafficking of ceramide Biochim Biophys Acta. 2007 Jun;1771(6):644-53._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/18165232">10: Saito S, Matsui H, Kawano M, Kumagai K, Tomishige N, Hanada K, Echigo S, Tamura S, Kobayashi T. Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes J Biol Chem. 2008 Mar 7;283(10):6584-93. </a>_x000D_ _x000D_ <strong>Products Related to Human CERT Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>