(+) -Norcisapride
(+) -Norcisapride (Ticalopride) is a potent 5-HT4 agonist and a 5-HT3 antagonist. (+) -Norcisapride has activity in animals models of constipation[1].
Product Specifications
CAS Number
202590-69-0
Product Name Alternative
Ticalopride
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/plus-norcisapride.html
Purity
99.32
Solubility
DMSO : 40 mg/mL (ultrasonic)
Smiles
O=C(N[C@H]1[C@@H](OC)CNCC1)C2=CC(Cl)=C(N)C=C2OC
Molecular Formula
C14H20ClN3O3
Molecular Weight
313.78
References & Citations
[1]Liming Shao, et al. mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I) . Bioorg Med Chem Lett. 2009 Oct 1;19 (19) :5679-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Apolipoprotein D; lactoferrin
Available Sizes
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