Propyl gallate
Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal. Propyl gallate exhibits anti-inflammatory, antitumor and cardioprotective activities[1][2][3][4].
Product Specifications
CAS Number
121-79-9
UNSPSC
12352005
Hazard Statement
H317, H318
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/propyl-gallate.html
Purity
99.85
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(OCCC)C1=CC(O)=C(O)C(O)=C1
Molecular Formula
C10H12O5
Molecular Weight
212.20
Precautions
H317, H318
References & Citations
[1]Cui H, et al. Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress. Food Chem. 2018 Nov 1;265:227-232.|[2]Wang J, et al. Scavenging of Acrolein by Food-Grade Antioxidant Propyl Gallate in a Model Reaction System and Cakes. J Agric Food Chem. 2019 Aug 7;67 (31) :8520-8526.|[3]Park WH. Propyl gallate induces cell death in human pulmonary fibroblast through increasing reactive oxygen species levels and depleting glutathione. Sci Rep. 2024 Mar 5;14 (1) :5375.|[4]Park WH. Propyl gallate reduces the growth of lung cancer cells through caspase‑dependent apoptosis and G1 phase arrest of the cell cycle. Oncol Rep. 2020 Dec;44 (6) :2783-2791.|[5]Du CK, et al., In vivo effects of propyl gallate, a novel Ca (2+) sensitizer, in a mouse model of dilated cardiomyopathy caused by cardiac troponin T mutation. Life Sci. 2014 Jul 25;109 (1) :15-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
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